Wii nunchuck mouse

You can get this functionality by sending the nunchuck data to the pc over the serial port and having a program on the PC control the mouse cursor.

There are a few articles on how to send nunchuck data to a pc, this one uses processing to receive the data:
http://www.arduino.cc/playground/Main/WiiChuckClass
Instead of displaying the position in Processing, you would need to use the java api to inject mouse events, see: JDK 20 Documentation - Home

If you prefer to use a windows programming language, the low level windows API function to insert keyboard and mouse events into the input stream is called SendInput: