Why should be an issue? I have 2 mega's 2 uno's a handful of pro-mini's and currently 3 bare 328's running code through 3 different USB devices... I am using Win 7 Ult, a 6 core AMD 6100 @ 3.3 GHZ and 8 gig's of ram. I run 1.0, 1.01 and the ERW 1.03 IDE's. ALL with no issues whatsoever. If the drivers for the USB devices are properly installed there should never be an issue using any Arduino board or FTDI adaptor... and all work the same on my little OLD Dell D610 laptop running Win7 Ultimate 32bit...
Bob