I think I may have got it! I was able to fit a 2-pin 0.1" header right near the 3.3V power line, with the idea being that when the user wants to use the FTDI interface, they can remove the jumper and cut off power to the Bluetooth module. Would this solve the RX/TX conflict issue and protect the Bluetooth module?
In the attached screen shot, the new header is in the top left, just next to the Bluetooth module.
