It depends, what are you trying to do an interrupt for? If you just want an interrupt on one of the pins, use attachInterrupt(pin, function_name) and detachInterrupt(pin).
The Due supports arbitrary interrupts on all pins...you are not limited to 2 or 3 or 4 (or whatever the Uno has.)
If you are talking about timers that's substantially different and more complicated and has been discussed extensively here:
exedor:
It depends, what are you trying to do an interrupt for? If you just want an interrupt on one of the pins, use attachInterrupt(pin, function_name) and detachInterrupt(pin).
The Due supports arbitrary interrupts on all pins...you are not limited to 2 or 3 or 4 (or whatever the Uno has.)
The Uno also supports interrupts on more than 3 pins. The limiting factor on the Uno is that you still only have 3 interrupt vectors.
The user still needs to figure out which pin was interrupted.
This library makes it easier, but possibly at the cost of response time. http://playground.arduino.cc/Main/PinChangeInt