Can you use the arduino usb2serial lite as a ISP

twice:
I do not have any arduino board, I have just an USB to serial cable, the PC and avrdude.

Is there a software that allows avrdude to program directly an empty AVR (without any bootloader preloaded) using the RS232 signals CTS, DSR, DCD, RI as MISO, SCK, MOSI, RESET, respectively?

No.