Arduino 101 Error: device not responding.

@DrGee

If you have any antivirus or similar security try installing the drivers with it turned OFF
Also try that method to see if you can do an upload.

DO stick with the USB 2.0 ports as they are more reliable.
Try other USB cables as they can go bad at any time.

There was a driver from Intel themselves that I found useful on occasion.
But DO NOT use the firmware from that page !