Win 10 has had some issues for some people with CH340/341 devices.
Most common remedy's are :-
Turn off driver enforcement.
Ensure you can see the COM & LPT ports in device manager.
Install drivers as ADMINISTRATOR (not just a user with admin privileges).
Turn off Antivirus and similar just to do the driver installs and check the uploads work as expected.
Ensure you are using USB 2.0 ports (USB 3.0 can on occasion cause issues).
If it not your own computer get your IT department to raise your user privileges or install the drivers for you.
For the FTDI device make sure you check the above issues first. as there was an FTDI issue over a year ago and I am unsure if windows fixed it or not.
In both cases check you have the latest drivers from the official sources.