avrdude: stk500_getsync(): not in sync: resp=0x00 on Sanguinololu

spcomputing

I'm running 023 Arduino ide
upon looking looking closer the 644p it is not. It is a atmega 1284p pu1247 this is (board 2) (board 1 is the 644p board 1 it is set aside for now)
I'm going back to check things to see what deference this makes
as far as the TinyIsp I have not tried it on (board 2) I need to study up on the use of it. I am not sure about the fuse thing (how to change)
but it sounds good.
One more thing (board 2) has never been in the printer its on the bench no 12 v power just usb power no stepper diver boards plugged in.
Is this OK. I've never been able to talk to it
Thanks for your time rji006