I2C - Analog

A MarkT in a different thread said this:

The CS pin (pin 3) must be held logic-HIGH to use I2C mode - if you don't do this is probably won't work (datasheet isn't
clear on this)

Check SDA is connected to pin 5 and SCL to pin 4. Tie pin 6 low via a 1k resistor to ensure consistent I2C addressing
BTW.

Could anyone offer up and more explanation on this - I'm just not clear on what he meant there.