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I used pcb way on the 4chip z80 board that iv e been playing with. I wasn't quite so lucky on postage, but I was impressed by quality and overall speed of delivery.
I've never used more than two layers.
The Z80 board has a Z80, a memory chip (64k), and an ATmega32 (running arduino code) that does front-panel-like things, bootloading the Z80, and all the IO. It's currently running BASIC, figForth, and CP/M.
All the details are here: A 4$, 4ICs, Z80 homemade computer on breadboard | Hackaday.io