Take a look at the limits of I2C/SPI signal lines, and then compare that to TTL-level serial. Then there's the issue of dealing with a serial-type chip that doesn't even have I2C/SPI.
Take a look at the limits of I2C/SPI signal lines, and then compare that to TTL-level serial. Then there's the issue of dealing with a serial-type chip that doesn't even have I2C/SPI.