serial rate of 921600 bps with arduino due ??

15bytes at the beginning of every millisecond.

That is 15 *10 * 1000 = 150.000 baud.
921600bps is a factor 6 above that (quite some safety margin

I have successfully used 345600 baud on an UNO so I expect no problem with the DUE as it is faster but I have not enough DUE experience.