16x16 RGB LEDs with 96 register, good idea?

I don't have this information maybe it was already agreed to use the 7219/7221s.

I see this phenomena when I have the controller on a different PCB than the LED matrix.
10cm to 15cm wire are enough at MHz frequencies to ecounter things like crosstalk, and noise pickup.
Eventually I use frequencies upto 8 Mhz not continuously but for some transitions.