Thanks for the replies so far.
kg4wsv, my perfboards already have the screw terminals soldered in, so for the time being I can't switch to pin headers (good suggestion for the future though). Are you sure a 22 gauge ferrule will not fit?
Also, how do terminals with greater pitch improve the situation? Are you saying the hole size changes as well? At any rate, I'm using perfboard with 0.1" spacing.
Doc, do you have a link to that "preferred" wire you are talking about? Bear in mind my setup involves about 100 feet of cable altogether.