There is also a project for extending the arduino's reach within the PC via some coding,
http://arduino.cc/playground/Interfacing/GoBetwinoGoBetwino is kind of a "genreric proxy" for Arduino. It's a program running on a PC (Windows only), that will act on behalf of Arduino and do some of the things that Arduino can't do on its own.
Sound like this could read a file on the PC on behalf of the arduino so it gets the information (number of unanswered e-mails).
I haven't tested it myself and I noted that the source code is quite old. Perhaps isn't updated for never Arduino and need some polishing.