If you have Bluetooth enabled, disable it. This is the most common issue with your error.
I just installed this build and got this error as well on a Windows 7 64 bit machine. (Just received my DUE today )So I experimented some, and I went into my Arduino Sketchbook directory and renamed my Hardware directory to some other name and now it runs.My hardware directory contains stuff to run for Arbotix Robots on an Atmega644p processor...So if you have a Hardware directory try removing it and see if that helps.Kurt
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