That power supply has 100uA leakage current, so you'd be best to ground the 0V output otherwise it'll
float at some sizable fraction of mains ac voltage.
Thanks for that. I hadn't considered that. The only question is do I have to worry about bypassing the RF filter?
Is not -5VDC but rather 0VDC or GND.
Tying that ground to earth is fine in my opinion.
The labels on datasheets are confusing sometimes. I thought it should be 0V originally, but they labelled it +Vo and -Vo, so I thought Vo was a constant 5V. Thanks for the clarification.
I'd be thinking of how I was isolating that second hot wire actually, it's still an exposed core within the cable.
The second hot wire just does a u-turn on the board and goes to a set of output terminals. I have well over the 0.4mm isolation required between routes.
Thanks for all your help!