Which macosx_setup.command did you run? I think you need to use the script from Processing (not the one from Arduino), as RXTX changed some things between the version in Arduino 0003 and the newer one in the latest versions of Processing.
Ok, Releasing the Reset button before clicking on Upload results in the error, 'Programmer is not responding', and the previously uploaded program continues running on the board prior to either green LED flashing. (speculation: which suggests to me that the upload is taking too long to commence and some form of timeout is occurring?)
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