How about this - route pin 21 up around the power connector, the FTDI connector, between Reset & the 2nd pin, to a pad on Port D connector (where the S in reset is).Most Crystals are ~4mm tall - that is low enough to fit under a DIP part in a socket? I wouldn't have imagined that would fit.
@theloonYou are using MCP1702 regulator. Data sheet says 250 mA Output Current for Output Voltages >= 2.5VSo wont that be a problem when say output pins starts providing more current? Please correct me if I am wrong..
Run the pin 21 trace between the FTDI's DTR and TX pin.Caps also seem oddly sized - C2 & C6 are both 0.1uF, yet have different footprints.C5 & C7 are physically smaller 22pF caps, yet also have large footprints. C1 & C4 are 1uF and typically physically larger, yet have small footprints too.I also know parts are available in all kinds of shapes & sizes tho, so these are just observations and not something that is necessary to change.