Robustness and long term reliability of Arduino boards and AVR chips

How long can the arduino or those AVR/PIC chips run continuously? Say blinking LEDs on Pin 1. How long can it last until it skips a beat or stops working properly or downright fails?

For example, if you make an RFID door to unlock it for a home automation application, you'd want the ensure your controller is quite reliable lol.

Yeah thats interesting too. I always wondered what chips industrial PLCs use. Do they use commercial ones manufactured by large fab houses or do they program their own controllers with FPGAs, ASICs, etc?