Daisy-chaining transformers just increases the losses, so isn't useful unless you need
the intermediate voltage as well. Good mains transformers are 80% to 98% efficicient (the
highest efficiciencies being for large power-distribution network transformers).
In power distribution there are often several stages of transformer daisy chained because
different parts of the network run at different voltages (2.75MV for national grids, 110kV
for underground cables, 11kV for overhead poles to rural users and city blocks, 240/220/110V for domestic consumers. But if you just want to change voltage at one location a single
transformer is cheapest to make and cheapest to run.