I used expressPCB for my first board, a simple 20 LED board arranged in 3 sections with 3 transistor drivers, a 4th transistor as a line receiver/signal inverter, and 7805 for 12V to 5V power supply. The signal was the TX from another board going to a promini, as was the 5V. The promini drive the 3 transistors. (A single 7406 would have worked as well, but I had this drawer of 1980's era transistors I wanted to finally use).
When my designs got more complex, I moved to eagle. The expressPCB rubberbanding leaves something to be desired. Eagle was awkward at first, so many parts options, took some getting used to.