ROM-Reader for Super Nintendo / Super Famicom Game Cartridges

If you look at the first post of this topic you'll see that the project started out on an Arduino Uno. So sure it's possible. And yes, all analog pins are used as digital input/output.

It just depends on how much your time is worth to yourself. The Arduino Uno does not have enough pins so you will need to add shift registers and do major changes to the current code.
Compare that to just buying an $8 Arduino Mega and I think you have your answer.