Tips for multi-voltage shield with I2C/SPI/Serial

I'm designing a shield for a mega2560, but I'd also like to be able to use it on a Due. It's almost all communications devices. For this first revision I'm using a lot of breakout boards. Here are the devices and their voltage tollerances.

  • Serial 1 - Signals at same level as Vcc. Perfect. I wish they were all like this
  • Serial2 - Again, signal = Vcc.
  • Serial3 - 5v only. Would need level shifter with Due
  • I2c #1 - 3v3 only, needs level shifter with Mega2560
  • i2c#2 - 3v3 only, needs level shifter with Mega2560
  • i2c#3 - Adafruit DS1307 RTC breakout board. Looks like 5v.
  • i2c#4 - 5v only, leeds level shifter with Due.
  • SPI - Adafruit uSD breakout. Says it will work at either voltage

Questions:
Do I power devices which can use either voltage from IOREF?
I know how to handle the I2C bus with two voltages by putting a level shifter between them, but what to do about the micro-controller needing to be on the low side of the bus (Due) to the high side? Jumpers/DIP switches?
For serial I was going to use a TXB0108 to convert from Serial3's 5v signal to a Due, but what about when it's 5V to 5V? Best I can come up with is pulling the breakout and replacing it with jumpers.

You might want to look at what digistump (makers of digispark ATtiny85 and digix Arm boards) did in their level shifting shield. Or perhaps you can use it as is: DigiX Level Shifter Shield - Digistump

Thanks,

It's as I suspected, they use level shifters and DIP switches.