OK, I'll do the research, and set it up with the right ifdefs.
I chose the DUE, because I'm going to use a 7-inch tft touch display. I'm using it as a master to control and monitor other units that manage aquariums, brewing fermentation, and some other things. Those basic units are simple, with temp sensors and relay controls. I was running out of room on my Mega that has been doing the job, and just added RF24 communications to already existing XBee communications. I'm also adding some very simple temperature monitoring only units.
So far, I have xBee, RF24, ds18b20 temp sensors, Ethernet, relays, and a simple display working.
Waiting for the new tft display and w5200 based Ethernet to arrive.