Android tablet case with joysticks?

Is it possible for me to build an Android tablet case with joysticks? Parallax has this: http://www.parallax.com/Store/Accessories/HumanInterfaceDevices/tabid/822/CategoryID/90/List/0/SortField/0/Level/a/ProductID/581/Default.aspx

I found out that there will be an IPad case with joysticks: http://www.audojo.com/

Did you have an Arduino question hiding in there somewhere?

If I want to build an Android tablet case with joysticks, how can I connect the Arduino UNO board to the Android tablet? I have Samsung Galaxy Tab 7.0 Plus tablet. It requires an USB to tablet adapter. http://www.samsung.com/us/mobile/galaxy-tab-accessories/EPL-1PL0BEGSTA

While I think this is possible, I also think the Android side programming would be daunting to say the least. I also think that it is likely to not be compatible with every game/app out there since not all game developers will use the same code behind to handle their joystick inputs.

If you google Android joystick, there are some really nifty stick on joysticks that can be had on the cheap that would serve the same purpose.