arduino and access

If the PC is running Windows then you can use Gobetwino to access files on the PC, and/or execute commands and return their output.

If you don't use Gobetwino then you will need to write your own equivalent to run on the PC and send/receive messages via the Arduino serial connection. If the application you're using to edit the data is something you developed yourself then it would be possible to have that receive and return the data via the serial connection directly.