Arduino IDE not working in Windows 10

cmayer777:
com.sun.jna.platform.win32.Win32Exception: The system cannot find the file specified.

This indicates that for some reason the Arduino IDE is unable to access your Documents folder. Maybe that folder is on a drive that is not currently accessible. Maybe it's a permissions problem.

It's best to find the true solution for the problem but if you can't do that, here's the workaround:

  1. Install the hourly build of the Arduino IDE from:
    http://www.arduino.cc/en/Main/Software#hourly

  2. Run it in portable mode by following these instructions:
    https://www.arduino.cc/en/Guide/PortableIDE

Reference: Arduino IDE fails to start under windows if "Documents" directory is unavailable. · Issue #7097 · arduino/Arduino · GitHub