Arduino Mega 2560 Clone upload problems

After I upload a sketch to my Arduino 2560, I can't upload anything else on it until I burn the boot-loader again on it using another Arduino. I searched the forums and the internet and I was unable to find a solution.

Thanks in advance for all your help !

Which version of the Arduino IDE are you using?

I’m using Arduino IDE 1.6.8

Try it with Arduino IDE 1.6.7 to see if that helps.