Arduino Mega 2560

Dear , I'm new here in the forum and would like to congratulate you for the initiative . I want to put myself in the provision of you who need it.
I wanted to share with you a problem I'm facing . Normal programming was the mega 2560 when I got the message when compiling :
Binary sketch size: 4560 bytes (of a 258048 byte maximum )
avrdude : stk500v2_ReceiveMessage ( ) : timeout
avrdude : stk500v2_ReceiveMessage ( ) : timeout
avrdude : stk500v2_ReceiveMessage ( ) : timeout
avrdude : stk500v2_ReceiveMessage ( ) : timeout
avrdude : stk500v2_ReceiveMessage ( ) : timeout
avrdude : stk500v2_ReceiveMessage ( ) : timeout
avrdude : stk500v2_getsync ( ) : timeout communicating with programmer
After several attempts , I thought my board was burnt . I continued on the same computer compiling programs in UNO board normally. I bought 2 new Mega 2560 boards . When compiling the first time , everything normal. after that never gave the same problems before. I took the other plate , installed the Arduino on another computer , I changed the cable and the same thing happened , ie , compiled the first time and then never again . I believe this is not a defect , but a problem related to the compiler for the Mega 2560, but not yet found what it is. Some of you already have this problem ? Can you help me ?
Thank you in advance . :frowning: