arduino mega impossible to upload sketch

hello, i got an arduino mega, and from a few days i cant upload my sketch,

the error: avrdude: ser_open(): can't open device "\.\COM12": access denied

avrdude: ser_drain(): read error: Handle invalid

thank you.

Post a link to where you got it from or a picture of the board then we can help you get the drivers loaded.

hey, i got the led tx and rx up when im uploading the sketch, but i get time out() i think it is a port problem but i dont know.