I find the solution in the forum. Here is the link
Go to File-Preferences. Click on more preferences can be edited ... C: \ Users \ user \ AppData \ Local \ Arduino15 \ Preferences.txt.
Close Arduino IDE.
Open the Preferences.txt and delete all the content and save it empty.
This will automatically correct the preferences when you open the Arduino IDE
Then, reinstall the Arduino Mbed OS Nano board in the Boards Manager.