Thanks for the advice. That board seems like a great option but unfortunately, the processer on the Nano BLE sense runs on nrf52 architectures which is not supported by the library I want to use (MIDIUSB.h - compatible with avr, sam, samd architectures).
I think you're correct that the best option is to have a wired prototype for communication and power, and to not use arduino for the final product.
Thanks so much for your help!