arduino pro mini - upload sketch problem

Hello ,
I think I play with something in the setting - and now I can't upload sketch , I'm getting this error:

stk500_recv() : programmer is not responding

I'm using Arduino IDE 1.6.7
with this setting :
board: arduino pro or pro mini
processor : ATmega328(5V,16Mhz)
Programmer : AVRISP mkll

I have try to uplaod to 3 pro mini devices
get the same error

what am I missing?

Thanks,