Your problem is not very clear. If it is software, the Bluetooth Bee is just a very expensive package for the common-or-garden HC-0x bluetooth module and should work the same way as any other HC-0x.
If it is mechanical, which should be obvious, the Bluetooth Bee is designed to fit on a Bee Shield and there should be no problem using that shield in conjunction with any other shield so long as there is no clash of pins - which is unlikely. The Bee Shield is made to accommodate more than one Bee device, and that may offer you a better option for whatever wireless device you have in mind.
I believe the Bluetooth Bee has standard pin spacing, thereby enabling you to install it on any prototyping shield.