Arduino UNO cannot upload

Arduino: 1.8.1 (Windows 10), Board: "Arduino/Genuino Uno"

Sketch uses 928 bytes (2%) of program storage space. Maximum is 32256 bytes.
Global variables use 9 bytes (0%) of dynamic memory, leaving 2039 bytes for local variables. Maximum is 2048 bytes.
avrdude: ser_open(): can't open device "\.\COM1": The system cannot find the file specified.

Problem uploading to board. See for suggestions.

This report would have more information with
"Show verbose output during compilation"
option enabled in File -> Preferences.

There is almost zero chance of your board being on COM 1.
Check in Device Manager for the correct port and apply that in the IDE.

If you dont see anything else under Com ports then you may need to do a driver install