Arduino UNO with BigSur and Apple M1 chip

Arduino IDE 1.8.16 sometimes give this error:
avrdude: stk500_getsync(): not in sync: resp=0x00
I just upload the program multiple times until it works.

Create Agent won't work. Give installations error all the time om Safari.
On Crome and Firefox is it possible to install the driver, but the boards is never found.
MacBook Air (M1, 2020)
macOS Monterey version 12.0.1