Atmega 328 bootloader or not?

Can you expand on that? I'm still a bit confused.

If I were to get one without the bootloader can I place it on the Uno (without using the other chip) and upload a program to it? Once it's uploaded, can I then remove the chip and solder it to a PCB that is set to recieve the Atmega328 with the 16Mhz crystal and capacitors and have it work?