Hi all,
I intend to make a project using arduino mega 2560, but the Arduino board is too big for the aplication. Can I burn bootloader on ATMega2560 and use in breadboard like the ATmega328p of Arduino UNO ??? 
Sure, if you can get the pins on the 2560 chip in the holes of the breadboard. You are going to have to make a breakout or buy one..
codlink:
Sure, if you can get the pins on the 2560 chip in the holes of the breadboard. You are going to have to make a breakout or buy one..
I know...
My intention is upload a scketch to a ATmega2560 stand-alone.
Are you using an Arduino as ISP? Than yes.
As long as you have a programmer, basically.
You might look at
http://www.pjrc.com/store/teensypp.html
I just created a tutorial that touches on this. Its based on the work done by many contributors to this forum. It shows how to breadboard and program an atmega 2560 using the minimum amount of components. You can find it at Programming the atmega 2560 with the Arduino IDE – kevinfundarek