avrdude: stk500v2_getsync(): timeout communicating with programmer

Hello, could not make sense of the already existing solutions

following problem:

Funduino Mega 2560 has yesterday working smoothly. Today I wanted to try a "blink", does not work.

I have chosen the correct port / board but when I want to install the program comes:

avrdude: stk500v2_ReceiveMessage (): timeout avrdude: stk500v2_ReceiveMessage (): timeout avrdude: stk500v2_getsync (): timeout communicating with programmer

the "on" -led lights and flashing if the rx led is over played briefly.

work with mac ... what else can I check?

thank you wfm

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-Malhar