Blind Assist

We are planned to make a blind assist device combining Ultrasonic sensors for object detection , Gps tracking and navigation and RFID reader for boarding public transport. can we combine these to an arduino uno. Is there any complication while connecting these..

In principle, you can combine these devices with an Arduino.
Identify the devices you want to connect, identify the libraries to support these and identify the Arduino type you wish to use. Check for things like pin (and other resource) conflicts.
Come here with a more specific list of devices and you may get a more specific answer.