Can Arduino IDE debugger be used for sketches that need to use TinyUSB

Continuing the discussion from Debugging on the new Nano ESP32:

This is good news, thank you.

Just a question for clarification:

The debug guide says to put the board in Hardware(CDC) mode and not Normal(TinyUSB) mode. Does this mean that sketches that need to use TinyUSB, eg. serial MIDI sketches, cannot use the debugger?

Yes, unfortunately. To be able to inspect the CPU at such low level, a dedicated hardware channel has to be used for the USB link, removing the possibility of additional software control. Only the CDC serial port and JTAG intefaces are exposed in this mode.