Can't upload to my Arduino UNO Board

Arduino: 1.6.5 (Windows 7), Board: "Arduino Uno"

I have checked the driver and it is up to date but the simple Blink file will not upload to the board. Below is the Error file I copied from the software window. I am running Windows 7 and Arduino software Ver. 1.6.5. When I first loaded the software onto my computer I had no problems uploading to my Uno boards, but now I can't get anything to upload, even the simplest program files like Blink.
I have been having this problem for the past 2 years. I have tried everything that I could think of, but nothing works.
Listed below is the error file I copied from the Arduino software error message.
Can anyone help me. Thank You!

avrdude: stk500_getsync() attempt 6 of 10: not in sync: resp=0xe9

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 7 of 10: not in sync: resp=0xe9

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 8 of 10: not in sync: resp=0xe9

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 9 of 10: not in sync: resp=0xe9

avrdude: stk500_recv(): programmer is not responding

avrdude: stk500_getsync() attempt 10 of 10: not in sync: resp=0xe9