You set voltage to 5volt, or 12volt, or whatever you think is safe when the LED is NOT connected.
And set the voltage limit to a safe value if/when the LED string gets open circuit.
That is very silly. If the led string gets to be an open circuit what is the danger? If it is below 50V then it is safe. Under what circumstances will 5V be safe when 12V is not? Remember a child’s electric train set has extensive exposed rails with 12V on them and no one (yet in this safety mad era ) thinks they are not safe.
Like I said they don’t actually understand electronics.
Back when I started a TTY machine would have 300V on the driving lines when not connected and about 3V when it was. That was an 80mA constant current loop system. If you restricted that to 50V then it would not have worked over the required distance.