Coldtears LCD TFT

Has anybody used one of these... Could this be driven by a UNO or maybe a large Arduino?

Probably not. It’s a USB “device”, like the arduino itself; designed to be connected to a “big computer” (the “usb host.”) Most arduinos can only be devices, and only talk to hosts.

An Arduino MEGA ADK might be able to talk to it; it has a “host” interface. I’m not sure of the complexity of the USB “display” protocols; it may be asking a lot for even an ADK to create meaningful displays…