Conductor not Responding (MPR121 Capacitive Shield)

ITO film - I had to look it up, is a plastic film with Indium Tin Oxide coating (apparently conductive, wouldn't expect that from an oxide).

You didn't explain how exactly you want to use that film, or how that shield works. Don't know why you need a complete shield for a capacitive touch sensor as all you really need is a high value resistor and a bit of software magic. They're remarkably simple.

Capacitive sensors can normally sense proximity (if not, increase your resistor size - 10 MOhm or more is usually needed to make proximity sensing work).

Your film: is that conductive only over the surface (as a coating would suggest), or also through the bulk to the other side?