Changed to a second device and same persists. I think It's time to review all the wiring and go back to the spec sheet for the device to make sure I'm not missing something very obvious.
EDIT: I'm making progress, as it turns out I had misinterpreted a setting from the device's spec sheet. The write protect pin was set to 5VDC and as soon as I changed it to ground the other two bytes showed up on the oscilloscope. The Device is now acknowledging the commands and I can see the rest of the pulse train that is supposed to be going to going down the bus. Now I'm just not seeing the change in the multimeter that I have connected to the set-up to verify the resistance is changing.