This may not be possible, but thought it worth pursuing. I do have some experience with Arduino, as I customized a guitar effect pedal and added MIDI control to it, and am not afraid to dig in deep to accomplish my goals. Here's my thread from a year or so ago on my previous project: Virtual, variable resistors, with saved presets recallable by MIDI - General Electronics - Arduino Forum
The current scenario is: I have a guitar floor processor (a Line 6 Helix) which has a USB-B type jack, and will accept a connection from an iOS device using an Apple Camera Connector Kit adapter, or direct connection to a computer. When the iOS device is connected, an 8x8 digital audio interface is established between the two, allowing audio to go in either direction. When directly connected to a computer, the guitar processor shows up as an audio interface in the computer's OS (so it becomes an available sound card).
I assume the iOS device is acting as a computer (a "USB Host" maybe?), and the guitar processor is acting as a "USB Device". Although I may be getting these terms completely wrong.
What I would like to investigate is, the possibility of building an Arduino powered device which can connect to the USB-B jack on the guitar processor, and accept a stereo audio signal (like an 1/8" stereo input jack), then convert the analog audio to digital audio, and send it to the guitar processor on USB audio 1/2 channels.
I assume this is more complicated than just converting analog audio to digital, as the host-to-device relationship connection would need to be made between the guitar processor and the Arduino as well; and I believe this relationship connection is where the complexity lies.
Is an Arduino even capable of doing this? There really isn't any other solutions for this, other than connecting the guitar processor to a computer, and then conecting the analog audio source to the computer; but that isn't very portable. And even the iOS device solution doesn't allow for an analog audio source to be passed into the guitar processor.
The end goal is to have something small and portable to enable analog audio to be sent into the guitar processor over the USB audio input.