Differential Air Pressure sensing (Guidance needed)

I think you're trying to get blood from a stone. The MPXV7002DP states a 2.5% accuracy in its output, or about 6 bits of accuracy.

That depends on whether hemilshah is looking for 13-bit accuracy, or 13-bit resolution. He wrote earlier:

if I have a pressure difference of say 0.1 or 0.001 kPa,will it be able to detect it?
Because I'll be using this to detect small pressure variations.

To me that suggests he needs to know if his pressure has changed by an amount in the order of 1Pa, not that he can measure to an accuracy of 1Pa. I don't know what he's measuring pressure for, but his process may be more sensitive to variation than to the actual mean value of pressure difference.

But of course, if he needs better than 2.5% accuracy, then he'll either need to calibrate or pick another sensor.