It depends on what you mean by "debugging". Unlike on the classic Nano, pins 0 and 1 on the Nano 33 BLE are Serial1, which is separate from the Serial interface used to communicate with the computer over the USB cable. So if you can use Serial for your debugging then pins 0 and 1 are free to use for other things.
We need to know which library you are using. for the TFT.
Again, we need to know which library you are using.